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The enzyme 5-Amino-1MQ blocks does not track body fat. It tracks insulin resistance. Non-diabetic individuals at BMI 33 had normal NNMT levels. And in the population where NNMT is elevated, exercise and dietary change bring it right back down, making 5-Amino redundant. NAMPT outcompetes NNMT by 430:1 regardless. A different NNMT inhibitor does ...
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